Jul 11, 2024 · Mast cell activation syndrome (MCAS) is when your mast cells overreact with no known trigger. It causes severe symptoms and can lead to life-threatening anaphylaxis.

Mast Cell Activation Syndrome (MCAS) happens with repeated symptoms of anaphylaxis – allergic symptoms such as hives, swelling, low blood pressure, difficulty breathing and severe diarrhea.

May 27, 2024 · Mast cell activation syndrome, also called MCAS or mast cell activation disorder, is a condition that causes mast cells to release high amounts of chemicals into your body.

Symptoms of MCAS are caused by excessive chemical mediators released by mast cells. [10] Mediators include leukotrienes, histamines, prostaglandin, and tryptase.

Feb 24, 2025 · Inflammation flares can be confusing. Learn how to identify and alleviate symptoms of mast cell activation syndrome (MCAS).

Apr 1, 2025 · MCAS is part of a spectrum of mast cell disorders involving abnormal function, non-clonal proliferation, accumulation, or activation of mast cells. It results in a wide range of allergic and …

Nov 3, 2025 · Mast cell activation syndrome (MCAS) is a disorder in which mast cells, a normal type of cell found in your immune system, release excessive amounts of histamines and other chemicals …

MCAS is a rare disease that is mostly diagnosed based on clinical symptoms. Here, we summarize recent developments about this disease, which is rapidly increasing in the frequency of diagnosis …

Primary MCAS happens when a group of mast cells in the body grows abnormally due to a genetic change. This can be linked to conditions like mastocytosis or Monoclonal Mast Cell Activation …

5 days ago · Struggling with unexplained allergic-type symptoms? Learn how allergists diagnose mast cell activation syndrome (MCAS) and why it’s often missed.