Centromeres play virtually the same central role across the entire tree of life: They ensure the faithful segregation of chromosomes during cell division. Yet the striking diversity in centromere ...

A research team at the IPK Leibniz Institute has developed a method that enables the detailed observation of female ...

Cell division is an essential process for all life on earth, yet the exact mechanisms by which cells divide during early embryonic development have remained elusive – particularly for egg-laying ...

Researchers at the Max Delbrück Center and the University of Oxford have found that a cellular housekeeping function called autophagy—by which cell components are broken down and recycled—plays a ...

Researchers at the Max Delbrück Center have found that a cellular housekeeping mechanism called autophagy plays a major role in ensuring that T stem cells undergo normal cell division. The findings, ...

This valuable paper describes a comprehensive quantitative phospho-proteomic analysis of Xenopus oocytes during meiosis. Using time-resolved proteomic analyses, the authors provide insights into ...

Spermatogenesis in mammals is crucial for male fertility. It starts after birth and continues throughout life, relying on spermatogonial stem cells (SSCs). SSCs can differentiate into early ...

The centromere of chromosomes plays a crucial role in cell division. Using the model plant Arabidopsis thaliana, an international team of researchers has investigated how two crucial proteins -- KNL2 ...

The two proteins KNL2 and CENP-C are crucial for the correct separation of chromosomes during cell division. To dock to the centromere, the newly described additional binding regions (DNA-b) to the ...